What is Cosmelan? Cosmelan is a product that can treat all types of pigmentation, such as melasma , post-inflammatory pigmentation , age spots and freckles. Cosmelan is a peel procedure to reduce surface pigment, followed by a special skincare regimen to reduce pigment over three months. The Cosmelan Depigmentation Peel is a unique, multi-ingredient chemical procedure designed to significantly reduce areas of hyperpigmentation and skin discolouration. What are the main benefi